British scientists have condemned the "monster" experiment allegedly created by the world's first genetically modified babies in China.
Dr. Jean Jianqui said he had made twins unable to get HIV infected by banning the CCR5 gene, which allows the deadly virus to enter human cells.
He says he did so in two girls called Nana and Lulu, who were born in China a few weeks ago, although the study was not published or independently confirmed.
This is illegal in many countries, including the United Kingdom, where scientists and ethics blame the researcher for a "very irresponsible, unethical and dangerous" science similar to "genetic roulette roulette."
People without CCR5 gene can be protected from HIV but are at greater risk than other viruses, including hepatitis B and West Nile virus, as well as dying of influenza.
Experts say editing genes also puts babies in greater danger of severe birth defects and cancer.
Dr. He, from the Southern University of Science and Technology in Shenzhen, has appointed HIV-positive men and their partners to treat fertility by offering them to protect their children from the virus. The chances of the father who transmits HIV are near zero when the mother is not infected.
Pairs receive fertility treatment and the CRISPR-Cas9 gene is injected into the sperm of the mother with the sperm. This acts as a molecular scissors to "pull out" the CCR5 gene that triggers protein to allow HIV in the cells.
Dr. He said that 16 out of 22 embryos were edited and 11 were used in six IVF trials before a woman got pregnant with her twins.
Dr. Hey's experiment, unveiled at an international genocide editing conference in Hong Kong, was described as "monstrous" by Professor Julian Savulescu, director of the Oxford Waheiro Center for Practical Ethics at Oxford University.
He said: "This contradicts the decades of ethical consensus and guidelines for the protection of human subjects in research, and in many other places around the world this would be illegal, punishable by imprisonment.
"These healthy babies are used as genetic guinea pigs, genetic genetic roulette."
Dr. Dusko Ilic, of the Faculty of Natural Sciences and Medicine at the Royal College of London, said: "These people have to face a criminal process – they experiment with children's lives without a reason to do it.
"Genesis technology is not perfect and … it can cause birth defects, from spina bifida to mental disabilities, and create genetic diseases that we have never heard of."
The fear of genome editing is that CRISPR-Cas9, composed of a homogeneous molecule and a sciatic DNA-reducing protein, can reach a zero level by increasing the risk of other diseases by introducing genetic mutations.
However, Dr. Es's team said the cells were removed from the embryos obtained, and babies, when they were born, showed that gene editing works safely.