Tuesday , June 22 2021

Vinculon was a member of Alzheimer's disease, a bacterium that caused one enfermedad dental syndrome



An estudio of the Universidad de Louisville halló a vínculo entre la P. gingivalis, which causes gingivitis and is a factor of respiratory and coronary heart disease, and enfermedad. También comprobó is likely to reduce the bacterial preservation of the cerebro ratones.


He's got Alzheimer's a mystery los mayores from medicine. In addition, the investigators have been investigating the issue of causation, which is a neurodegenerative disorder, which is caused by the causation of muerte in the mundo, which is a disease that affects the affluence of the aument. Entre las nuevas hipótesis, un estudio publico une idea alarmante: puede que el Alzheimer sea una infección.

And to the prospect no ese novedosa, there is a concrete pathway that has a type of bacteria especifica: Porphyromonas gingivalis, a Gram-negativo cocobacillus that causes cronica parodontitis, a gingivitis.

He microbiologist Jan Potempa, from the Université de Louisville, has been conducting an equipo que hallowe bacteria en cerebros de pacientes que murieron de Alzheimer. In addition, it has been shown that the experimental challenge has been made with the use of beta-amyloid proteins in the production of beta-amyloid proteins and the association of Alzheimer's associations.

One monster from the manifestación del Alzheimer en el cerebro humano. (Getty)

En la investición participante Stephen Domina, cofundador de la startup Cortexyme. At the pharmacy, he has been doing the same thing as a drug that has been impeding the proliferation of toxins from P. gingivilis. Según su eficaccia, it undergoes a treatment, a hasta a vacuna, against bacteria; which is not equivalent to a vaccine against Alzheimer's disease, is an important factor in the investigation of therapies.

"Yet, it has been known that infectious agents have been deserted and progressive in Alzheimer's disease, the evidence for the causal cause of no congestion," the Domino and Science Alert. "Ahora, in the first place, is the phebos cell that connects the intracellular pathogen, the gram-negative P. gigivalis, and the origin of the Alzheimer's disease".

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Además, el equipo halló en el cerebro de los pacientes muertos por esa enfermedad las enzimas tóxicas que secreta la bacteria, llamadas gingipaínas, en correlación con marcadores independiente del mal, la protein de la marcador de proteinas ubicuitina.

It is dissociated from the causas del Alzheimer. One nueva hippocampus analysis is injecting one bacterium.

The cerebral examination of personas que no sufrieron Alzheimer antes de su muerte, los científicos encontraron menores niveles de P. gingivalis, is under consideration in a warning message: en caso de haber vivido més, podrían haber desarrollado la enfermedad.

"At the same time, the diagnosis of Alzheimer's disease was diagnosed with Alzheimer's disease and the diagnosis of a diagnosis of malignant disease, and that he was not suffering from malignant dysplasia of the salud dental debian comienzo de la demencia, ni una consecuencia de las etapas finales de la enfermedad, sino una manifestación temprana ", escribieron en el trabajo.

This is a good example of the drug Cortexyme, the COR388 lymph, which is currently undergoing a study of patients with Alzheimer's disease. It utilizes en ratones, which is able to reduce bacterial cannabis and a P. gingivalis cerebellar infection, and reduces the production of beta-amyloids and inflammation of the thymus.

The bacterium P. gingivalis, responsible for gingivitis and asocide and many inflammatory infections, admás del infarto de miocardio, under the estar en la razz del Alzheimer. (Wikipedia)

The Sin embargo, "lacks drugs against bacterial proteins from the bacteria, has been used by many people," David Reynolds, director of Alzheimer's Research. "Pero dado que has 15 years to go, and it is important to treat the dementia, which is important for the enormous challenges posed by the detention of enfermedades como el Alzheimer".

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It has been shown to be distinct in the accumulation of protein amyloidases and to the cerebellum, which has been proliferated as long as 10 years ago, 20 years before which stenosis occurs. Y and bien es possibil tener placas amiloides sin sufrir demencia, los científicos han produit de controllaar en las des produits de tratamente. It is estimated that the protein is a defensate against the bacteria, which is the only way to control it: it eliminates the microorganism that causes it.

In P. gingivalis no solo causa gingivitis: también is a factor that is a factor for the peripheral nervous system inflammation, pulmonary infections, myocardial infarction, arteriosclerosis y anticipation del parto.

Fuente: Infobae


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