Thursday , November 26 2020

Parents praise peanut research, which proves that you can build tolerance for allergies



A new study found that it is possible to build tolerance for peanut allergies.

Parents have praised the study, which has found that participants, usually unable to tolerate exposure to even one-tenth of allergens, can handle two whole peanuts.

Children who suffer from severe allergies took part in the one-year study, which was given increasing amounts of peanut protein.

Now used to treat pollen, he hopes that immunotherapy can protect people from life-threatening reactions, Mirror reports.

Emily Pratt has created tolerance
Emily Pratt has created tolerance

A mother of a six-year-old girl who participated in the trial said she "completely changed her life."

Sophie Pratt said, "Before we participated in Emily, we were uncomfortable when we were more than twenty minutes from a hospital, and she could not attend parties or parties without me or my husband being there.

"We had to constantly study food labels to ensure that peanuts are completely removed from Emily's diet.

Her allergy was very heavy, so even a small amount of peanuts could cause a very serious reaction. The impact on our family life was enormous. "

The 44-year-old said that by the end of the year, Emily had managed to take about seven peanuts.

The PALISADE study has raised nearly 500 children aged four to 17 years from the US and Europe to participate in the largest attempt to treat allergic peanuts.

Participants were divided into groups that received either a peanut protein capsule or a dummy powder.

Doses gradually increase every two weeks for a period of six months before continuing to maintain a "maintenance dose" of peanuts for another six months.

The results, published in the New England Journal of Medicine, show that about 67% of children and teenagers can tolerate at least 600 mg of peanut protein, compared with only 4% of placebo participants.

The survey gave parents hope
The survey gave parents hope

Professor George de Toth, a pediatric allergy consultant at Evelina London and the principal investigator of the study, said: "Peanut allergy is extremely difficult to manage children and their families because they have to follow a strict diet without peanuts.

"Families live in fear of accidental exposure because allergic reactions can be very severe and even lead to death.

"Until recently, there was nothing to offer peanut allergy except peanut avoidance education and self-treatment of allergic reactions."

Peanut allergy, a potentially life-threatening condition, has doubled over the past two decades and affects about 1 in 50 children in the UK.

Allergy is rarely exaggerated and is the most common cause of death of food allergies.

The PALISADE study is funded by Aimmune Therapeutics, which produces peanut protein, used during the trial, and was conducted by researchers from the Evelina London Children's Hospital and King's College London.

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