Wednesday , December 2 2020

Researcher Urban Urban – UOH received a research project from the Chilean Society of Endocrinology and Diabetes



In addition, Dr. Paulina Ormazabal of the Institute of Health Sciences presented some preliminary results corresponding to this new study line at the XXIX SOCHED Congress which took place in Coquimbo.

Dr Paulina Ormazabal, Academy of Sciences, received funding from the Chilean Society for Endocrinology and Diabetes (SOCHED), which aims to promote the development of clinical, basic clinical or clinical epidemiological studies in endocrinology and diabetes, which can serve as a basis for research lines or more advanced future projects.

Dr. Ormazabal is applying for the fund with his project "Effect of the Plant Lampaya Medicinalis Phil. on the activation of JNK and the levels of TNF-α and FABP4 induced by fatty acids in human hepatocytes HEPG2 & quot ;, which represents a new branch within the framework of the UOH academy's study of the beneficial effect of the endemic plant from the Chilean mountains, Lampaya Medicinalis, against inflammation caused by fatty acids in the liver cells.

"With these tools, I can choose to evaluate new molecular markers of inflammation through much more specific and sensitive laboratory techniques," Dr. Ormazabal explained.

Regarding the importance of granting this fund, the researcher stated that "this is recognition of the research work being developed within the framework of the UOH This work aims to confirm the ethno-pharmacological knowledge of the use of medicinal plants for the treatment of diseases In particular, this study will investigate a phenomenon commonly encountered in obesity, which is consistent with the inflammation of the liver due to the accumulation of fat inside the liver cell.This is transcendental when overweight weight and obesity are conditions of high prevalence on a national and global scale and unfortunately our region does not slip out of this reality. "

Scientifically confirmed that Lampaya Medicinalis It has an anti-inflammatory effect, it will have a great impact on the local and national level as it is a native Chilean plant and may offer its use as an additional therapy for the treatment of liver inflammation related to obesity and obesity.

Within the first five of the SOCHED Congress

Dr. Ormazabal also presented preliminary results corresponding to this new study line at the XXIX SOCHED Congress, which took place in Coquimbo municipality between 8 and 10 November.

The title of the work presented to Congress is "Effect of Hydroalcoholic Extract from the Andean Plant Lampaya on in vitro-induced steatosis in human hepatocytes "

In this case, work was selected among the top five in the field of translational endocrinology.

This study is the result of the multidisciplinary work of chemists, biologists and biochemists. The extract from Lampaya Medicinalis It has been prepared and donated by researchers from the Biochemistry Laboratory of the Antofagasta Institute of Antofagasta University and the experiments are conducted in INTA's Obesity, Metabolism and Aging Laboratory.

It should be noted that in October this year the ICS academician received the "SOCHINUT – Henri Nestlé 2018" Science Development Award, which aims to support and popularize researchers who, with their active and innovative work, contribute to improving the quality of life of the nutrition, nutrition and health of Chile – with its research project "Protective Effect of Lampaya medicinalis Phil. on Fatty Acid Steatosis and Hepatic Inflammation in Human Hepatocites HEPG2".

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