Monday , January 18 2021

Stem Cells May Be The Key To The Treatment Of Children With Autism – Vida Actual – Latest News From Uruguay And World Updated



"Some studies have shown that there are cells in the umbilical cord that express proteins that simulate neurons that help to form new connections between them," said Ouedda.

The World Health Organization (WHO) defines Autistic Spectrum Disorders as a group of conditions characterized by some degree of disruption of social behavior, communication and language, as well as a limited stereotyped repertoire of interests and activities. repeating.

Autism is not considered a disease but a disease that affects 1% of the world's population.

The Department of Health calculates that in Mexico there are almost 95,000 children between zero and four years of age with ASD.

This is a neurological condition that affects the behavior, interaction and learning of who has it.

"It has so far been known that in some genes there may be patterns that are repeated in autistic patients, as well as failures in the regulation of the immune system, inflammation of the brain, or differences in the brain structure of patients." – said Ouedda.

The complexity of the afflictions caused by this condition complicates the standard treatment for it; However, American researchers have found hope to treat autism that has no cure.

Autism affects 40 out of every 10,000 people,
Photo: Archives

"It has long been observed that stem cells, under certain conditions, can release proteins known as neurotrophic factors that stimulate certain effects in neurons and the central nervous system," said the specialist.

However, he said, this does not mean that the cells become neurons, but they "send signals so that the neurons are activated and mature or form new connections that could potentially help develop the child's brain," said he.

The most recent study in this regard was conducted by American scientists from the Center for the Study of Autism and Duke's Brain who applied stem cells to 25 children aged 2 to 5 years diagnosed with ASD and then evaluated with behavioral tests

The cells used for this study are from the umbilical cord blood of children with ASD that parents have decided to prevent.

"What has been done is that through the intravenous cells these cells are taken as serum and by the signals that send the neurons can generate a connection between them," said the expert who has a Masters degree in "Technology" in the stem cells of University of Nottingham, UK.

He explained that this experimental treatment seeks to induce maturation, spread and formation of new neuronal connections that allow the child's brain to have a greater chance of development that is invariably dependent on its symptoms and the severity of the disorder.

Photo: archive of El País
Photo: archive of El País

This means hope, because nowadays treatment is "practical rehabilitation, therapies, but it does not generate as much improvement as in clinical trials."

This, he said, is just one example of a study that is done with umbilical cord stem cells that seek to find better treatment options.

He also stressed that this therapy is still in the research phase to generate safe, effective and reproducible treatments without adverse long-term effects.


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