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Sugar with mannose can improve cancer treatment

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Updated on 11/23/2018 – 10:44 o'clock

Keywords:cancer, treatment, sugar, mannose, improvement

Cancer Cells – Archives

London, 11/23/2018 (The People Online) – Some natural supplements, such as mannose, can help treat cancer. According to a study funded by Cancer Research UK and Worldwide Cancer Research and published today in Nature, this nutritional supplement seems to not only slow the growth of the tumor but also improve the effects of chemotherapy in multiple-type mice. of cancer, stresses ABC.

It is known that tumors use more glucose than normal and healthy tissues. However, it is very difficult to control the amount of glucose in your body with just the diet. In this study, the researchers found that mannose may affect glucose to reduce the amount of cells that sugar can use.

Professor Kevin Ryan, lead author of the Beatson Cancer Institute in the United Kingdom, says: "Tumors need a lot of glucose to increase, so limiting the amount they can use should slow down the progression of cancer The problem is that normal tissues also need glucose, so we can not completely remove it from our body In our study we found a dose of mannose that can block enough glucose to slow tumor growth in mice but not so much, that normal tissue is affected Annie. This is an early study, but we hope that finding that perfect balance means that in future Mannose can be administered to cancer patients to enhance chemotherapy without damaging their overall health. "

Tumors need a lot of glucose to grow, so limiting the amount they can use should slow the progression of cancer.

In the study, the researchers first explored how mice responded with pancreatic, lung or skin cancer when mannose was added to their drinking water and administered as an oral treatment. And they note that adding the additive significantly reduces tumor growth and does not cause any side effects.

To investigate how mannose can affect the treatment of cancer, mice are treated with cisplatin and doxorubicin, two of the most commonly used chemotherapy drugs. They saw that mannose improves the effects of chemotherapy, reduces tumor growth, diminishes the size of tumors, and even increases the life expectancy of some mice.

Similarly, other types of cancer, such as leukemia, osteosarcoma, ovarian and intestinal cancer, have been studied. Researchers cultivate cancer cells in the lab and then treat themselves with mannose to see if their growth is affected.

Some cells responded well to the treatment and others did not. It has also been found that the presence of an enzyme that degrades mannose in cells is a good indicator of the effectiveness of the treatment.

Mannose is sometimes used for short periods of time to treat urinary tract infections, but its long-term effects have not been studied. More research is important before mannose can be used in cancer patients.

In this sense, Martin Lewick of Cancer Research UK believes that although these results are very promising for the future of some cancers, "this is a very early study and has not yet been tested in humans." Patients should not prescribe mannose alone because there is a real risk of unwanted side effects that have not yet been studied. It is important to consult a doctor before dramatically changing your diet or taking new supplements. "

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