Wednesday , August 10 2022

Beware, immune malaria has spread to Southeast Asia


By: Eco P, Jakarta – There are types of malaria parasites that are resistant or immunized against the two major antimalarial drugs. Even malaria has spread to Southeast Asia with its dominant regions in Vietnam, Laos and northern Thailand, after it has spread rapidly from Cambodia.

Using genomic observations to track malaria-resistant treatment, the researchers found that malaria KEL1 / PLA1 parasite also evolved and absorbed new genetic mutations that made it more resistant to various drugs.

"We (the parasites) have spread aggressively, replacing local malaria parasites and becoming the dominant species in Vietnam, Laos and northeastern Thailand," said Roberto Amato, who collaborates with a team from the Sanger UK Wellcome Institute, Oxford University. and Mahidol University in Thailand, quoted by VOA, Wednesday (24/7).

According to the World Health Organization (WHO), nearly 220 million people are infected with malaria by 2017, and about 400,000 of them have died. Most infections and deaths occur in infants and children in sub-Saharan Africa.

Malaria can be fully cured with treatment if diagnosed early. However, resistance to anti-malarial drugs is increasingly prevalent in many regions of the world, especially in Southeast Asia.

The first malaria treatment that has been practiced in many places in Asia over the past decade is a combination of dihydroartemisinin and Piperakuin, or known as the DHA-PPQ abbreviation.

In a previous study, researchers found that a kind of malaria parasite had evolved and spread throughout Cambodia between 2007 and 2013. ,

"The prevalence of parasites to treat malaria in Southeast Asia is very worrying," said Olivet Miotto, who led the study.

"Other drugs may be effective at this time, but the situation is very vulnerable, and this study highlights the need for swift action," he explained. (Far / EP)

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