1.2 million people in the Netherlands suffer from type 2 diabetes. Scientists and doctors around the world are looking for a cure for this disease. Wednesday is World Diabetes Day. The right time to see how it is.
"Possible new drugs for diabetes", the title de Volkskrant three weeks ago, and other media reported "good news for type 2 diabetes patients". The reason for this is European research led by Annieke van Baar, researcher in gastrointestinal and intestinal diseases at Amsterdam UMC.
Burning the mucous lining in the duodenum can cause a better signal to the pancreas, with the result that the body becomes sensitive to the hormone insulin. Some diabetic patients therefore do not need to inject insulin.
This is the latest research in global diabetes research. Since the discovery of insulin in 1922, many new discoveries have been made about this disease. Wednesday, November 14, is World Diabetes Day. Every year attention is given to patients with diabetes and diabetes today.
Type 2 diabetes is an advanced disease
It used to be called old age sugar if someone has type 2 diabetes. According to endocrinologist and internist Hanno Pijl, who has conducted research on diabetes at the Leiden University Health Center (LUMC), this fact has long overtaken us. More and more children among patients.
What's wrong with type 2 diabetes is the action of the hormone insulin. Usually our bodies make hormones to transport glucose in the blood to the tissues. Glucose functions as food for, among other things, muscles. In diabetes 2 you do it, but the hormone does not function properly. The result: glucose cannot leave your bloodstream and because of this the level of glucose in your blood becomes too high.
Too high a glucose level is dangerous according to Arrow; your body wants to balance sugar levels that are too high. Because it does not work through the normal pathway, chronic low-level inflammatory processes occur. This inflammation causes damage to blood vessels. It's dangerous in the long run; diabetes increases the risk of diseases such as cardiovascular disease, stroke, cancer, eye and kidney problems and dementia.
To make the body more sensitive to insulin, general practitioners almost always prescribe pills. Then follow other drugs to increase insulin. Many diabetic patients therefore have to inject insulin. It often works.
However, Professor Pijl has doubts. High insulin concentrations have many side effects, they increase blood pressure. In addition, there are indications that they promote the growth of cancer cells.
Many diabetic patients must inject insulin to increase insulin.
Drugs do not address the core problem
With medicine, according to him, you often end up with rain in the infusion. In addition, they don't discuss the core of the problem: "You indirectly reduce blood sugar levels by increasing insulin, but do nothing about inflammation."
The good news is that work is being done on new solutions such as those at Amsterdam UMC? Yes and no, Arrow said. Research from Amsterdam seems to indicate that interventions can delay the use of insulin in people who must actually take medication.
After one year, 90 percent of the nineteen subjects in this study did not need insulin. Therefore it can be a way to bring the development of diabetes to a standstill, Arrow thought. But there are no long-term results. In addition, interventions do not improve the health of the subject.
Type 2 diabetes must be reduced and reversed
That's why professors ask for more lifestyle advice from general practitioners. Improving health is possible. Type 2 diabetes is always seen as a chronic disease that you never lose once you experience it. But that is not true. According to Pijl, this is one of the biggest inventions in recent years; diabetes must be reduced and even reversed. With good nutrition, lots of exercise, stress management and healthy sleep, many patients are able to reduce their sugar levels.
How is that possible? According to Pijl, lifestyle is one of the main reasons why the number of type 2 diabetes patients has increased dramatically in the past few decades. We come to life very differently from our ancestors from whom we inherited genes. We eat far more unhealthy and we are much fatter.
Overcome root problems
Overweight type 2 diabetes works at hand. According to scientists, this might be because the immune system causes the inflammatory process to focus on adipose tissue, especially in the stomach. In addition, fat cells as glands also produce hormones that neutralize the effects of insulin.
Losing weight is often very helpful, according to Pijl. Because cells lack fat, the fewer inflammatory reactions, the better the work of insulin. The chances of diabetes are reduced immediately if you lose weight. Even with a few pounds.
So, eat lots of vegetables and good fats, and leave products with lots of salt, sugar, and bad fats. Then you prevent mild inflammation. Moving also helps. Sometimes it is also needed to deal with stress better, and regular sleep also helps.
Some studies gave him the same thing; Type 2 diabetes patients who switch to a healthy lifestyle do not have to spray glucose again or no longer at all. According to Pijl, a drug to combat type 2 diabetes, because with your lifestyle intervention, you can overcome problems at the root
What is the difference between type 1 and 2 diabetes?
- In type 2, the body makes less insulin and the body does not respond to insulin properly because of insensitivity to insulin.
- Type 1 diabetes is an immune disease: often occurs in a short time in people under the age of thirty. The immune system becomes unbalanced and attacks the cells that produce insulin.
- One in ten diabetic patients has type 1 diabetes, nine others suffer from type 2 diabetes.