Sunday , July 25 2021

Hypertrophic cardiomyopathy | Genes for diseases that cause sudden death are found



It is very surprising to know that an athlete with a daily exercise routine suddenly dies. How is it possible if I live a healthy life? The answer lies in genes.

This type of sudden death is usually caused by a genetic inheritance of the disease called hypertrophic cardiomyopathy, which thickens the walls of the heart. According to Spanish Heart Foundation, heart love is present in 1 in 500 people.

So far, that is known Hypertrophic cardiomyopathy inheritedbut not what genes are involved. One new research, published in the American Collegue of Cardiology (JACC), showing that it is the FHOD3 gene.

Investigation It was developed for 3 years in more than 40 health centers distributed between Spain, England and Denmark.

"We found four families in a very small city in Murcia, Spain. This place has fewer than 30 thousand residents and we found that, even though they did not know it, they had a common ancestor that was passed down from seven generations ago. We genotyped more than 7 thousand patients. Then we identified mutations in 30 families and we followed them for a long time. In this way, we can connect FHOD3 with hypertrophic cardiomyopathy, "explained Juan Pablo Ochoa, who came from the team that discovered the gene. Argentine newspaper La Nación.

The hypertrophic cardiomyopathy This is indicated by produce arrhythmias and difficulty breathing on the affected, although it usually shows no symptoms.

Argentine researchers point out that this great discovery, besides being an advance in cardiovascular genetics, too will have practical objectives by enabling the development of screening techniques hypertrophic cardiomyopathy.


Source link