The NHS will allow people to pay for a report on their genetic plan that can predict serious health risks.
Genetic data will be used to compile a health report that may allegedly predict the risk of contracting a number of serious conditions such as cancer and dementia.
The initiative follows the launch of the 100,000 genome project in 2012.
This has led to tens of thousands of genetic plans sequenced by patients with cancer and rare diseases.
Genomic data are stored for the benefit of 85,000 patients who have contributed to their DNA and for supporting medical research.
Future customers who pay will be required to share their anonymous genetic data to support the Genomes project.
Health Minister Matt Hancock said: "Genomics has the potential to transform health care and I am very proud that the UK is the world's leading 100 000 genome project.
"I'm determined to do everything in my power to use this life-saving technology, so seriously ill children and adults with genetic diseases, including cancer, will be offered DNA analysis as part of their routine care.
And while healthy people do not have to use this service for free at the National Health Service, there are tremendous benefits in arranging as many genomes as possible – each genome that is sequenced approaches us to unlock life-saving treatments.
"So, along with that, we introduce genomic volunteering by offering people the opportunity to pay to map their DNA in return for voluntary donation of their anonymous data to help researchers develop treatments that will benefit all in the future. "
However, there are concerns about the plans, and the chair of the British Society for Genetic Medicine, Anneke Lucasen, said there was "a misunderstanding of what the whole sequence of the genome could do."
She told The Times: "She thinks this will give you clear clinical predictions, and most of the time.
"People tend to think the test is high risk or not, but without a family history of breast cancer, the predictions may be very uncertain."