The Tennessee Department of Health warned that a hepatitis A outbreak had killed one person and left more than 400 people sick.
The department said the outbreak was most severely affecting Nashville and Chattanooga.
Health Commissioner John Dreyzehner (DRYZ & nur) said in a news release that more than half of those identified with the disease needed hospitalization and more possible deaths.
Hepatitis A is a liver disease that is usually transmitted through contact with contaminated feces or consumption of contaminated food or water. The outbreak of Tennessee is linked to a large multi-country outbreak that began in 2017. This mainly affects drug users and people who experience homelessness.
Vaccines are available, and more than 36,000 doses have been given to those most at risk.