Cannabidiol may help people overcome addiction to heroin or opioids, according to a study by the Icahn Medical School in Sinai, the results show that CBD reduces anxiety and causes hunger, as published in the American Journal of Psychiatry.
Overdoses related to addiction have surpassed US-related deaths, heroin and opioid use has led to more than 300,000 deaths over the past decade, with their numbers rising and despite the unprecedented epidemic there are limited treatment options.
Methadone and buprenorphine are designed to work on the same opioid receptors as heroin, but they themselves are potentially addictive, making them strictly regulated, meaning that these treatments are inaccessible to many diagnosed with disorder.
"To respond to the critical need for new treatment options for millions of people and families who have been devastated by this epidemic, we have launched a study to assess the potential of non-toxic cannabinoids for thirst and anxiety in heroin-dependent individuals. The specific effects of CBD on drug-induced thirst and anxiety are particularly important in the development of addictive therapeutic agents, as environmental signals are one of the strongest triggers for relapse and prolonged drug use. explains Dr. Jasmine Hurd.
42 drug abusers took randomly either 400 mg of CBR; 800 mg CBD; or a corresponding placebo, participants were exposed to neutral and drug-related signals immediately after administration; 24 hours later; and 7 days after the third and last day of administration.
Drug-related signals were videos depicting drug use and related attributes, and neutral signals were three-minute videos of relaxing natural scenes; appetite measurements, anxiety, positive and negative affects, and vital signs were obtained at different times during the sessions.
CBD has been found to significantly reduce appetite and anxiety from drug signals; The positive effects of CBD have lasted 7 days after exposure, suggesting that the benefits of CBD as a treatment are long-lasting, even when CBD is not expected to be present in the body.
"Our findings show that CBD has significant promises to treat heroin-related disorders. A successful opioid-free drug would add significantly to the existing drug addiction toolkit to help reduce the rising number of casualties, the enormous healthcare costs, and treatment constraints imposed by stringent government regulations in this stubborn opioid epidemic.
The amounts used in this study are quite large doses, for daily pain, anxiety and other conditions, doses between 5-200 mg per day are considered sufficient to provide relief for some people.
CBD stimulates the endocannabinoid system that supports balance and body functions when unbalanced phytocanabinoids such as CBD can help rebalance the system to get it back to work.